Melanie is a Heart Foundation (Australia) Future Leader based in the Charles Perkins Centre at the University of Sydney. Her research group (Cardiometabolic Proteomics) focuses on understanding molecular adaptations in the heart in response to physiological challenges, including ischemia/reperfusion injury, cardiometabolic syndrome and diabetes. To investigate changes in protein, metabolite and lipids profiles her group uses mass spectrometry. Given the nature of these pathologies, they also use mass spectrometry to identify post-translational modifications important in the adaptation process, with a focus on phosphorylation and redox modifications. Her lab also specializes in the development of pre-clinical models, small animal imaging, cardiac physiology, and histology. At the completion of her PhD, Melanie was awarded a National Health and Medical Research Council (NHMRC) Overseas Fellowship at Johns Hopkins School of Medicine. Upon her return to Australia, she was funded by an Australian Research Council (ARC) DECRA fellowship. Melanie was the recipient of the Early Career Award (2011) from the Australasian Proteomics Society and is currently the Secretary of APS. She has been involved in the program committee of the annual Lorne Proteomics Symposium since 2019. Melanie was the first Australasian representative of the HUPO ECR committee and is passionate about mentoring the next generation of scientists as well as supporting mothers + fathers in science.