A top-down proteomic approach to the identification of early serum biomarkers predictive of spontaneous preterm birth — ASN Events

A top-down proteomic approach to the identification of early serum biomarkers predictive of spontaneous preterm birth (#242)

Arlene D'Silva 1 , Jens R. Coorssen 1 , Jon Hyett 2
  1. Discipline of Molecular Physiology and the WSU Molecular Medicine Research Group, School of Medicine, Western Sydney University, Sydney, NSW, Australia
  2. Department of Obstetrics, Gynaecology and Neonatology, University of Sydney, Maternal Fetal Medicine Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia
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  1. Wright, E.P., et al. (2014) Top-down proteomics: Enhancing 2D gel-electrophoresis from tissue processing to high sensitivity protein detection. Proteomics 14, 872-889.
  2. Butt, R.H., Coorssen, J.R. (2005) Postfractionation for Enhanced Proteomic Analyses: Routine Electrophoretic Methods Increase the Resolution of Standard 2D-PAGE. J. Proteome Res. 4, 982-991.
  3. Gauci, V.J., et al. (2013) Coomassie blue staining for high sensitivity gel-based proteomics. J. Proteomics 90, 96-106.
  4. Wright, E.P., et al. (2014) Deep Imaging: How much of the Proteome Does Current Top-Down Technology Already Resolve? PLoS ONE 9(1): e86058. doi:10.1371/journal.pone.0086058.