PROTEOMICS 2016* Pre-Lorne Workshops
WEDNESDAY 3rd FEBRUARY 2016
3D STRUCTURE DETERMINATION BY MASS SPECTROMETRY
Time: 9:00am – 3:45pm Location: The Bio21 Institute, The University of Melbourne, Victoria
Confirmed Speakers
Prof. Andrea Sinz, Martin-Luther University Halle-Wittenberg, Germany
– Cross-linking and mass spectrometry for structure determination
Dr. Tara Pukala, The University of Adelaide, Australia
- Ion mobility-mass spectrometry for structure determination
Assoc Prof. Ganesh Anand, National University of Singapore, Singapore
- HDX mass spectrometry for structure determination
Program
9:00-9:15 am Registration and Welcome
9:15-10:00 am Ion Mobility Mass Spectrometry: An Added Dimension for Structural Biology.
Dr Tara Pukala, The University of Adelaide, Australia
10:00-10:55 am Dynamics of Macromolecular Assemblies by Amide Hydrogen/Deuterium Exchange Mass
Spectrometry: From protein-ligand interactions to signalling particles.
A/Prof Ganesh S. Anand, National University of Singapore, Singapore
10:55-11:15 am Coffee Break
11:15- 12:00 pm Chances and Pitfalls of Chemical Cross-Linking and Mass Spectrometry.
Prof Andrea Sinz, Martin-Luther University Halle-Wittenberg, Germany
12:00-1:00 pm Lunch break
1:00-1:45 pm Native mass spectrometry; practical consideration, experimental optimisation and current
limitations.
Dr Tara Pukala, The University of Adelaide, Australia
1:50-2:30 pm HDXMS: Practical considerations and opportunities for complementarity with orthogonal
biophysical and computational approaches
A/Prof Ganesh S. Anand, National University of Singapore, Singapore
2:30-2:45pm Coffee Break
2:45-3:30pm Practical Aspects of Cross-linking and Introduction of StavroX/MeroX Software.
Prof Andrea Sinz, Martin-Luther University Halle-Wittenberg, Germany
3:30-3:45 pm Concluding remarks
Proudly Sponsored by 
THURSDAY 4th FEBRUARY 2016
Mass Spectrometry ‘101’ Tutorial Series
Presented by: Dr. Nicholas Williamson
Mass Spectrometry and Proteomics Facility, Bio21 Institute, The University of Melbourne
Time: 12:30pm - 3:30pm Location: Heritage 2, Mantra Lorne Lunch: Provided
This pre-conference lecture aims to provide a basic working knowledge of mass spectrometry, proteomics and simple proteomic bioinformatics. It is deliberately aimed at novice users with little or no prior experience in the field. Explanations are kept as simple as possible. Emphasis will be placed on understanding the broad concepts that will be assumed knowledge during the conference.
Mass Spectrometry ‘202’ Tutorial Series
Presented by: Prof. Gavin E. Reid
School of Chemistry, Department of Biochemistry and Molecular Biology, Bio21 Institute, The University of Melbourne
Time: 12:30pm - 3:30pm Location: Heritage 3, Mantra Lorne Lunch: Provided
This pre-conference lecture will provide a more advanced understanding of the underlying principles of mass spectrometry and tandem mass spectrometry methods applied to proteome analysis, with an emphasis on the characterization of PTM’s and quantitation. It is aimed at those people who have previously taken part in the Mass Spectrometry ‘101’ Tutorial Series (or its equivalent), or users with some prior experience of the field.